The survival time of patients mostly depends on the fact whether metastases form or not. Therefore, it’s extremely important to use apigenin besides medicinal mushroom extracts as the combined use of these two components is a well known method for treatment of cancers.

Apigenin is a plant pigment which protects the plant from various pathogens. It seems that it’s able to keep its defensive effects in the human body as well. Apigenin can be produced from vegetable and fruit extracts. The highest amounts can be found in watermelons, melons, celery and chamomile but a lot of other fruits and vegetables contain it.


Apigenin is one of the most common flavonoids. Apigenin is easily absorbed into our bodies and in a couple of weeks all of our cells and tissues can become saturated with it. This flavonoids protective function even has effects on the whole body.

There have already been clinical trials about apigenin in Germany which lasted 5 years. The number of patients wasn't incredibly high as only 20-30 patient participated in the study. In the case of those operated with bowl cancer those who regularly used apigenin extracts the illness mostly disappeared, the protection rate was over 90%. On the other hand those that did not use apigenin extracts in 50% of the cases the disease recurred. The phenomenon prompted cancer researchers that the effects of apigenin for cancer patients are worth taking advantage of.

It’s clear that apigenin can be essential in the treatment of cancers.

The cancer researchers also suggested that apigenin could be used as a food as it’s commonly known that there will never be a commercial drug made from apigenin since we are talking about a common vegetable pigment flavonoid. Therefore, the licensing procedures will never approve it as a drug despite the fact that its positive health effects significantly overtake those of conventional drugs and therapies.

As a result of this, in almost all cases the use of apigenin is recommended with the combined use of medicinal mushrooms as this increase the effectiveness of immune therapies and significantly lowers the side effects of radio and chemotherapy thus increasing the chances of their success. In the case of such treatments an optimal side effect profile can be achieved.

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With all cancer therapies the most important step is always the prevention of metastases and the stabilisation of the patient’s condition. If we could prevent the formation of metastases then the patients general mood and their condition improves and these significantly determine the survival time of the patient.

Numerous scientists and researchers compare the success of apigenin and chemotherapy treatments. In many areas the two treatments are equal as well as apigenin not having any of the adverse side effects.

The body has a lot of growth factors which could have metastasis-inducing effects. Such as vascular endothelial growth factors (VEGF) but they are effectively inhibited by apigenin. This phenomenon is far from negligible since this growth factor is responsible for the formation of blood vessels around tumours and thus it plays a role in 'feeding' the tumour. Consequently the tumour cells are able to disperse in the human body which leads to the formation of metastases and therefore further complicating further treatments.

At the same time apigenin enhances the effectiveness of immune therapies as these growth factors are also responsible for the immune systems inability to recognise and detect the presence of cancerous cells. Since apigenin inhibits the function of these cells it supports the immune systems correct functioning.

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The immune activator effect of medicinal mushroom extracts significant increase when use combined with apigenin. It’s most important role is in prevention especially in those periods when we don’t have the opportunity to continuously consume sufficient amounts of apigenin rich fruits and vegetables. A good example of this is watermelon, whose consumption in seasonal periods allows our bodies to become saturated with apigenin. However, if this process stops the flavonoid in our bodies is completely depleted in 2 weeks.

In addition of numerous advantages of apigenin it also acts as an internal sunscreen. In the case of melanoma it plays a major role in the protection against the sun.

If our tissues are saturated with apigenin they are able to exert defences against the development of metastases. In the case of skin cancer this is very significant as it can also provide excellent defences against man-made electrical radiation. Therefore in simple terms; the use of apigenin can increase our body's internal defence system against the effects of a variety of cancers.

Clinical observations and experiments have shown that the combined use of apigenin and medicinal mushroom extracts resulted in the patient’s condition drastically improving. Whilst taking the correct medicinal mushroom extract is effective and for many patients may be sufficient the combined use of these two products resulted in noticeably better results as the patient’s condition and their wellbeing equally improved.

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